مشخصات پژوهش

عنوان	Environment assisted quantum model for studying RNA‑DNA‑error correlation created due to the base tautomery
نوع پژوهش	مقاله چاپ‌شده در مجلات علمی
کلیدواژه‌ها	Adaptive Mutation, Dissipative Environments, Quantum Model
چکیده	The adaptive mutation phenomenon has been drawing the attention of biologists for several decades in evolutionist community. In this study, we propose a quantum mechanical model of adaptive mutation based on the implications of the theory of open quantum systems. We survey a new framework that explain how random point mutations can be stabilized and directed to be adapted with the stresses introduced by the environments according to the microscopic rules dictated by constraints of quantum mechanics. We consider a pair of entangled qubits consist of DNA and mRNA pair, each coupled to a distinct reservoir for analyzing the spreed of entanglement using timedependent perturbation theory. The reservoirs are physical demonstrations of the cytoplasm and nucleoplasm and surrounding environments of mRNA and DNA, respectively. Our predictions confrm the role of the environmental-assisted quantum progression of adaptive mutations. Computing the concurrence as a measure that determines to what extent the bipartite DNA-mRNA can be correlated through entanglement, is given. Preventing the entanglement loss is crucial for controlling unfavorable point mutations under environmental infuences. We explore which physical parameters may afect the preservation of entanglement between DNA and mRNA pair systems, despite the destructive role of interaction with the environments.
پژوهشگران	فاطمه قاسمی (نفر اول)، آرش تیرانداز (نفر دوم)