مشخصات پژوهش

عنوان	Electrochemical study of 2-amino-5-mercapto- 1,3,4-thiadiazole in the absence and presence of pbenzoquinone: an efficient strategy for the electrosynthesis of new 1,3,4-thiadiazole derivatives
نوع پژوهش	مقاله چاپ‌شده در مجلات علمی
کلیدواژه‌ها	Electrochemical study of 2-amino-5-mercapto- 1,3,4-thiadiazole in the absence and presence of pbenzoquinone: an efficient strategy for the electrosynthesis of new 1,3,4-thiadiazole derivatives
چکیده	In this study, first, the electrochemical behavior of 2-amino-5-mercapto-1,3,4-thiadiazole (AMT) was fully investigated in the absence and presence of electrochemically generated p-benzoquinone (p-BQ, which is the oxidized form of hydroquinone), as an electrophile, via cyclic voltammetry (CV) at a glassy carbon electrode (GCE) and in an acetic acid buffer (0.2 M)/ethanol solution mixture. Then, an E–pH diagram was proposed for different structures of AMT at various pH values. The obtained voltammograms also exhibited an “electron transfer + chemical reaction” (EC) mechanism. Besides the voltammetric exploration, electrosynthesis of new 1,3,4-thiadiazole derivatives was conducted by constant current electrolysis (CCE) as a facile and cost-effective method for the formation of S–S and S–C bonds. Finally, the biological activity of products was also analyzed via an in silico method.
پژوهشگران	حسین معصومی (نفر اول)، صادق خزل پور (نفر دوم)، مهدی جمشیدی دهنوی (نفر سوم)