|
چکیده
|
In recent years, metal-organic frameworks (MOFs) are known as a new group of porous materials that have high design ability due to the variety of ligands and metals [1]. These frameworks have properties such as ultra-high surface area, adjustable pore size, adjustable inner surface and charge conduction [2]. Zirconium metal is one of the important nucleus in design of MOFs with biological properties and stability. Zr based MOFs present different topologies such as bcu, csq, ftw and fcu according to the ligands used in their structure [3]. For this purpose, BDC-NH2 is one of the most important ligands in the structure of Zr based MOFs. The post-modification method is very interesting for the design of various catalysts based on metal-organic frameworks (MOFs) [4]. Due to the biological structure and post-modification of metal organic frameworks (MOFs) with phosphorous acid tags, we found a strategy for the preparation of UiO-66-NH2/Melamine/[N(CH2PO3H2)2]2 as a heterogeneous and porous catalyst by the condensation reaction of UiO-66-NH2/Melamine and phosphorous acid under EtOH reflux. This efficient and reusable catalyst was tested in the preparation of novel spiro-oxindole derivatives under refluxing CH3CN/H2O condition (Scheme 1). N-heterocycle compounds such as spiro-oxindoles have attracted much attention due to their application in solar cells and their medicinal properties such as human NK-1 receptor inhibitors, antitumor agents, antibiotics, anticancer and antibacterial [5].
|