مشخصات پژوهش

عنوان	Complexation of guanidino containing l‑arginine with nickel on silica‑modified Hercynite MNPs: a novel catalyst for the Hantzsch synthesis of polyhydroquinolines and 2,3‑Dihydroquinazolin‑4(1H)‑ones
نوع پژوهش	مقاله چاپ‌شده در مجلات علمی
کلیدواژه‌ها	Hercynite@SiO2-l-Arginine-Ni · Hantzsch reaction · Polyhydroquinoline · Cyclocondensation · 2,3-dihydroquinazolin-4(1H)-one
چکیده	In this study, a novel amino acid-based Ni complex was immobilized on SiO 2-modified Hercynite magnetic nanoparticles as the support to prepare the heterogenized guanidino-nickel catalyst (Hercynite@SiO2-l-Arginine-Ni). The uniform surface morphologies of these nanoparticles were characterized using SEM. Thermogravimetric analyses indicated that the [Hercynite@SiO2-l-Arginine-Ni] nanocomposite possessed reliable thermal stability. The homogeneous dispersion of nickel species on the surface of the amino acid-modified Hercynite was characterized using X-ray mapping and XRD. The catalysis studies showed that this heterogenized l-Arginine-Ni magnetic complex was highly active for the asymmetric Hantzsch synthesis of polyhydroquinolines and cyclocondensation of anthranilamide with aromatic aldehydes to generate 2,3-dihydroquinazolin-4(1H)-ones. In addition, the magnetic and heterogeneous nature of Hercynite core allows the easy separation of the catalyst by magnetic decantation. Besides, the [Hercynite@SiO2- l-Arginine-Ni] can be reused for at least 5 catalytic cycles for both of the mentioned reactions without an obvious drop in its activity
پژوهشگران	مسعود محمدی (نفر اول)، آرش قربانی چقامارانی (نفر دوم)