مشخصات پژوهش

عنوان	Synthesis of the novel nanomagnetic catalyst and its application in the synthesis of benzo-[h]quinoline-4-carboxylic acids via a cooperative vinylogous anomeric based oxidation
نوع پژوهش	مقاله ارائه شده کنفرانسی
کلیدواژه‌ها	Benzo-[h]quinoline-4-carboxylic acid, Anomeric based oxidation (ABO), Cooperative vinylogous anomeric effect, Multi component reactions, Reusable nanomagnetic catalyst.
چکیده	In the last half-century, quinoline derivatives have been extensively investigated due to their biological and pharmaceutical activities. It has been reported that quinoline derivatives widely served as antagonists, analgesic agents, 5HT3, NK-3 receptors, and structural subunits of natural products. Quinoline-4-carboxylic acids are one of the most important series of quinoline derivatives because they have a variety of medicinal effects and are applied as active components in industrial antioxidants. 1-3 Herein, we designed a novel and reusable nanomagnetic catalyst, which was synthesized and its catalytic application was examined at the synthesis of benzo-[h]quinoline-4-carboxylic acid derivatives via a three-component reaction (Figuer 1). Resulting experimental data suggest that the final step of the plausible mechanism proceed via a cooperative vinylogous anomeric based oxidation mechanism. The presented catalyst shows excellent potential of recycling and reusing at the described multicomponent reaction.
پژوهشگران	فاطمه کریمی (نفر اول)، میثم یاری (نفر دوم)، محمدعلی زلفی گل (نفر سوم)