مشخصات پژوهش

عنوان	Protective effects of Bacillus sp. MBIA2.40 and Gallipro on growth performance, ‎immune status, gut morphology and serum biochemistry of broiler chickens ‎feeding by Aflatoxin B1‎
نوع پژوهش	مقاله چاپ‌شده در مجلات علمی
کلیدواژه‌ها	Aflatoxin B1, Gallipro, Bacillus. sp, Aflatoxigenic, Broiler‎
چکیده	A total of 540 one-day old male broilers Ross 308 were allocated to 6 treatments in a ‎completely randomized designed with a 2×3 factorial arrangement (aflatoxin B1 (AFB1) and ‎probiotics) with 6 replicates and 15 birds in each. Factors include aflatoxin B1 (control, 500 ‎ppb) and probiotics (control, 108 cfu/mL Bacillus sp. MBIA2.40, 0.2 g Gallipro per kg). ‎Results showed that adding 500 ppb AFB1 to broiler diets resulted in a significant decrease ‎of body weight gain and feed intake (P < 0.05). The highest of feed conversion ratio was ‎observed in AFB1 group (P < 0.05). Average body weight gain was significantly increased ‎while feed conversion ratio decreased by Bacillus sp. MBIA2.40 and Gallipro compared with ‎control group (P < 0.05). The supplementation of Bacillus sp. MBIA2.40 and Gallipro in ‎contaminated diets relieved the negative effects of aflatoxin on performance . ‎ Increased serum ‎aspartate amino transferase, alanine amino transferase, alkaline phosphatase and lactate ‎dehydrogenase were observed in diet contaminated with AFB1 compared with other groups ‎‎(P < 0.05). The lowest antibody production against Newcastle disease and sheep blood cells ‎and also the lowest skin response to phytohemagglutinin were observed in the AFB1 group (P ‎‎< 0.05). Villus height and width were significantly increased by probiotics diets without ‎AFB1 in compared with others (P < 0.05). The crypt depth was significantly higher by birds ‎fed AFB1 rather than that others (P < 0.05). Improving villus height, width and crypt depth ‎by the diets containing probiotics + AFB1 were found as similar as the control diet (P > 0.05). ‎In general, the results of this study showed that adding of Bacillus sp. MBIA2.40 and ‎Gallipro in contaminated diets reduce negative effects of AFB1 and consequently these ‎probiotics (especially Bacillus sp. MBIA2.40) have a protective effect against aflatoxicosis in ‎broiler chickens.‎
پژوهشگران	منصوره عبدالملکی (نفر اول)، علی اصغر ساکی (نفر دوم)، محمدیوسف علیخانی (نفر سوم)