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چکیده
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The development of the efficient catalytic system for the selective oxidation of alcohols followed with the condensation reactions to the formation of C-C bonds is not only an interesting issue in basic chemistry research, but it is also a significant case for the chemical industry. Remarkable attempts have been dedicated towards the employment of waste-free and selective electrochemically mediated TEMPO-catalyzed oxidation of alcohols as an appealing and highly promising method for this type of transformation.1-3 Also, a literature survey shows different considerable methodologies which a carbonyl group undergoes nucleophilic attack in order to the formation of C-C bonds under the title of condensation reactions.4 But to date, and the best of our knowledge there has been no report of the in-situ simultaneous electrochemical synthesis of above-mentioned reactions. This elegant idea can be accomplished by the paired electrosynthesis strategy.5 Furthermore, metal-organic frameworks (MOFs) are the spotlight of a comprehensive research area, particularly in the modified electrode, with the eye-catching features of the large surface area and catalytic effects.6-9 In this work, we introduce the paired electrosynthesis of knoevenagel condensation by the HKUST-1 metal-organic framework modified electrode. To shed light on this issue, we used of anodic half-reaction for the in-situ electrocatalytic oxidation of alcohols to the related aldehyde and so of cathodic half-reaction for in-situ deprotonation of malononitrile by electroreduction of the protic solvent. In the following, the in-situ generated aldehyde undergoes nucleophilic attack by the activated methylene in the presence of MOF tin film (MOFTF) as a large surface substrate and known catalyst for condensation reactions. Implementation of this eco-design procedure as a one-step, base additive-free, and versatile protocol leads to the convergent paired electrosynthesis. In the other words, two different substrates unde
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