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چکیده
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In this project, a series of heterogeneous catalysts including functionalized magnetic Fe3O4 nanoparticles have been prepared and their catalytic activities in the synthesis of five and six-membered heterocyclic compounds have been studied. This project was performed in three experimental parts as following: In part 1, synthesis of hexahydroquinoline in the presence of nanomagnetic Fe3O4@SiO2@Propyl–ANDSA has been explored. This nanocatalyst can be easily recovered via external magnetic and reused without any significant drop in its catalytic activity. Easy preparation catalyst, uses water and ethanol, high yields and short reaction times are some advantages of this method. In part 2, synthesis and investigation of catalytic activity of Fe3O4@ SiO2@Si(CH2)3@melamine@ picolinealdehyde@ SO3H in the synthesis of pyrido[2,3-d]pyrimidine derivatives have been studied. High surface area and recyclability, use of solvent- free, easy preparation of the catalyst, low reaction times and high yields of the products are the main advantages of this method. In part 3, synthesis of pyranopyrasol in the presence of nanomagnetic Fe3O4@SiO2@melamine@SO3Hhas been explored. The advantages of these protocols include doing these reactions in as solvent-free conditions, short reaction times, high yields, simple workup and use of environmentally friendly solid substrates.
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