|
چکیده
|
Background: Brucellosis is a major bacterial zoonosis of global importance.The causative organisms are Gram-negative facultative intracellular pathogens that may affect a range of different mammals including man, cattle, sheep, goats, swine, rodents and marine mammals. In most host species, the disease primarily affects the reproductive system with concomitant loss in productivity of animals affected. Brucellosis is an important infectious disease of sheep and goats. B. melitensis is primarily responsible for brucellosis in sheep and goats. Brucellosis occurs in small ruminants in the Mediterranean and Middle Eastern countries, particularly Iran, and spreads eastward to southern regions of Russia, Mongolia and northern China. The majority of abortions in sheep and goats occurred in the last month of gestation. They can be of considerable economic importance to the sheep and goat industry. Methods: in this experimental study the sheep are used. Brucellosis vaccine strain Rev.1 was injected to sheep the subcutaneous method, and then blood sampling from sheep was taken on days Zero, 14, 30, 60, 90, 120, 150, 180 after vaccination and after getting blood serum, serological tests Wright and 2Me were performed. Results: In the six months that serological tests was performed, sheep have an antibody titer and the highest antibody titer was on day 14 and Least antibody titer was 180 day, and most amount antibody titer down happened On the day 60. Conclusion: At least 6 months after vaccination with brucellosis vaccine strain Rev.1, there are antibodies in sheep blood and after spending this time, it should also be investigated more than six months.
|