مشخصات پژوهش

عنوان	EVALUATION OF EXPRESSION OF TNF-Α, IL1-Α, IL1-Β PRO- INFLAMMATORY GENES IN LIVER LEISHMANIA INFECTED BALB/C MICE
نوع پژوهش	مقاله ارائه شده کنفرانسی
کلیدواژه‌ها	Leishmania, pro-inflammatory genes, liver,BALB/c mice
چکیده	Background and Aim: Leishmaniasis is a disease with different clinical symptoms. This study focuses on expression of pro-inflammatory gene. Investigating the expression of cytokines, especially in the liver, can be important in detecting the profile of inflammatory genes in cutaneous leishmaniasis. Methods: Expression of these pro-inflammatory genes including IL-1α, IL-1β, TNF-α was analyzed using by RT-PCR in liver Leishmania infected BALB/c mice. Results: Pro-inflammatory genes, including TNF-α, IL-1β were expressed in mice infected liver. Conclusion: Current study indicated a role for Leishmania in expression proinflammatory genes in livers of infected mice.
پژوهشگران	حسین رضوان (نفر اول)، سحر هامون نورد (نفر دوم)، مریم همزه ای (نفر سوم)، الهام قیاسوند (نفر چهارم)