|
عنوان
|
Solid phaseextractionofamoxicillinusingdibenzo-18-crown-6 modified magnetic-multiwalledcarbonnanotubespriortoits spectrophotometricdetermination
|
|
نوع پژوهش
|
مقاله چاپشده در مجلات علمی
|
|
کلیدواژهها
|
Amoxicillin Modified magnetic-multiwalledcarbonna- notubes Removal Preconcentration Spectrophotometricdetermination Solid phaseextraction
|
|
چکیده
|
This workreportsonamethodforselectiveextractionandsensitivedeterminationofamoxicillindrug (AMX). ThemethodisbasedonsolidphaseextractionofAMXbyanovelmodified magneticna- noadsorbent priortospectrophotometricdeterminationofAMXusingaprocedurebasedonformationa colored azo-derivativeoftheinvestigateddrug.Thenanoadsorbenthasbeensynthesizedbymodification ofmagnetic-multiwalledcarbonnanotubewithdibenzo-18-crown-6moieties.Thesynthesized nanoparticles werecharacterizedusingTEM,XRDandFT-IRmeasurements.Atthenextstep,various factors thatcouldpotentiallyaffectadsorptionanddesorptionefficiencies ofAMX,havebeenoptimized. The resultsshowedthatundertheoptimizedconditions,sensitiveandselectivedeterminationofthe investigateddruginconcentrationrangeof5.0–1000.0ngmL1 with thelimitofdetectionof 3.0 ngmL1 wasachievable.Furthermore,therealsampleanalysis(i.e.amoxicillincapsulesandhuman urine samples)resultsindicatedthatareliablepromisingcandidatemethodhasbeendevelopedforthe determination ofAMXintheinvestigatedrealsamples.
|
|
پژوهشگران
|
مظاهر احمدی (نفر اول)، طیبه مدرکیان (نفر دوم)، عباس افخمی عقداء (نفر سوم)
|