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عنوان
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Preparation of a ZnO nanoparticles/multiwalled carbon nanotubes/carbon paste electrode as a sensitive tool for capecitabine determination in real samples
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نوع پژوهش
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مقاله چاپشده در مجلات علمی
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کلیدواژهها
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چکیده
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The present study describes the fabrication of a sensitive electrochemical sensor for the determination of capecitabine (Cap). The zinc oxide nanoparticles/multiwalled carbon nanotubes (ZnO/MWCNT) modified carbon paste electrode (CPE) is proposed as a novel electrocatalytic system for the reduction of Cap. Scanning electron microscopy (SEM), X-ray diffraction measurements (XRD) and differential pulse voltammetry (DPV) were used to characterize the performance and microstructure of the sensor. The electrochemical reduction of Cap was investigated at the ZnO/MWCNTs/CPE by the use of DPV. The developed electrode exhibited excellent electrochemical activity towards the electrochemical reduction of Cap. The sensor shows a linear range from 0.10 mmol L1 to 100.00 mmol L1 with a detection limit of 0.03 mmol L1 at a signal to noise ratio of 3. The modified electrode has excellent analytical performance and can be successfully applied in the determination of Cap in biological systems
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پژوهشگران
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طیبه مدرکیان (نفر اول)، حجت قاسمی (نفر دوم)، اسماعیل حق شناس (نفر سوم)، عباس افخمی عقداء (نفر چهارم)
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