مشخصات پژوهش

عنوان	پAlum as a Catalyst for the Synthesis of Bispyrazole Derivatives
نوع پژوهش	مقاله چاپ‌شده در مجلات علمی
کلیدواژه‌ها	Alum; bispyrazole derivatives; 3-methyl-1-phenyl-1H-pyrazol-5(4H)-one; Carbonyl compound; Solvent-free conditions
چکیده	Compounds with pyrazolemoieties as nitrogen-containing heterocyclic systems have received attention owing to their diverse biological activities. Alum (KAl(SO4)2¨12H2O) is an inexpensive, reusable and nontoxic catalyst used to synthesize 1H-pyrazole derivatives via the reaction of 3-methyl-1-phenyl-1H-pyrazol-5(4H)-one and carbonyl compound under solvent-free conditions at 60 ˝C. The proposed method has been used for the preparation of 1H-pyrazole derivatives to yield green products for cleaning-in-place and to avoid toxic catalysts and hazardous solvents in accordance with the philosophy of sustainable chemistry.
پژوهشگران	محمدعلی زلفی گل (نفر اول)، اردشیر خزایی (نفر دوم)، فاطمه کریمی تبار (نفر سوم)