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چکیده
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[2,2'-Bipyridine]-1,1'-diium tricyanomethanide {[2,2'-BPyH][C(CN)3]2} as a novel nano structure ionic liquid catalyst was synthesized, characterized and applied for the synthesis of 2-aryl-5-methyl-2,3-dihydro-1H-3-pyrazolone derivatives by one pot four-component condensation between various aromatic aldehydes, ethyl acetoacetate, phenyl hydrazine and β-naphthol under solvent-free conditions at room temperature. The pyrazolone skeleton is exist in many antifungal,1 antimicrobial,2 antibacterial,3 anti-inflammatory4 and antitumor5 agents. Herein we composed the advantages of nanotechnology for designing of a new, green, and mild procedure for the synthesis of pyrazolone derivatives using {[2,2'-BPyH][C(CN)3]2} as a novel nano ionic liquid catalyst (Scheme 1). The scope and limitation of the described methodolgy will be discussed.
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