مشخصات پژوهش

عنوان	Electrochemical evidences for the reaction of N-acetyl-p-benzoquinone-imine with organosulfur compounds contained in garlic and onion extracts. Treatment of acetaminophen poisoning using garlic and onion extracts
نوع پژوهش	مقاله چاپ‌شده در مجلات علمی
کلیدواژه‌ها	acetaminophen poisoning; garlic extract; cyclic voltammetry; chronopotentiometry; chronocoulometry
چکیده	The electrochemical oxidation of N-acetyl-p-aminophenol (acetaminophen) (AC) has been studied in the presence of garlic and onion extracts using cyclic voltammetry, chronopotentiometry and chronocoulometry methods. The results revealed that the electrochemically generated toxic N-acetyl-p-benzoquinoneimine participates in the Michael addition reaction with organosulfur compounds contained in garlic or onion extracts and is converted to its reduced none toxic form(s). Based on these results, garlic and onion extracts can be useful for the treatment of acetaminophen poisoning before starting clinical treatments.
پژوهشگران	داود نعمت الهی (نفر اول)، بهاره فیضی برناجی (نفر دوم)، آمنه امانی (نفر سوم)