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چکیده
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Electrochemical methods are widely used for the study of electroactive compounds in pharmaceutical forms and physiological fluids due to their simple, rapid, and economical properties [1]. Unique selectivity because of in situ formation of an active species at the interface, inversion in polarity by transfer of electron and variability in product formation by control of potential are some of advantage of electrosynthesis. Michael addition reaction, as a one of the effective organic reaction, has been shown its importance during last years. Electrochemical oxidation of catechols has been studied in the presence of 4,6-dimethyl-2- mercaptopyrimidine as nucleophile in aqueous solution using cyclic voltammetry and controlled-potential coulometry methods. Among the numerous methods to synthesize substituted catechols, Michael-addition reactions play an important role. We derived catechol derivatives in good yields based on controlled potential electrochemical oxidation at carbon electrode in a divided cell.
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