عنوان
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Condensation of Aryl Aldehydes, 2-naphthol, and Thioacetamide Catalyzed by N-halo Reagents in Neutral Media
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نوع پژوهش
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مقاله چاپشده در مجلات علمی
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کلیدواژهها
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Multi-component condensation; 1,3,5-trichloro-1,3,5-triazinane-2,4,6-trione (TCCA); 1,3-dichloro-5,5-dimethylhydantoin (DCDMH); 1-thioamido-alkyl-2-naphthol; Solvent-free.
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چکیده
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A new three-component, highly efficient and solvent-free approach for the synthesis of known and new 1-thioamido-alkyl-2-naphthol derivatives was investigated. This was achieved via a one-pot condensation by reacting aryl aldehydes, 2-naphthol, and thioacetamide in the presence of catalytic amount of 1,3,5-trichloro-1,3,5-triazinane-2,4,6-trione (TCCA) and 1,3-dichloro-5,5-dimethylhydantoin (DCDMH). Mechanistically, the in situ generation of Cl+ ion from TCCAand DCDMH is proposed to catalyse the reactions in neutralmedia. In the presented work,most of the products have been reported for the first time.
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پژوهشگران
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اردشیر خزایی (نفر اول)، فاطمه عباسی (نفر دوم)، احمد رضا موسوی زارع (نفر سوم)، مرضیه خزایی (نفر چهارم)، حسن بیضوی (نفر پنجم)
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