مشخصات پژوهش

عنوان	Thermodynamic and Kinetic studies of complex formation reaction between deferiprone and iodine in organic solvents
نوع پژوهش	مقاله ارائه شده کنفرانسی
کلیدواژه‌ها	Kinetic, Thermodynamic, deferiprone, charge transfer copmlex
چکیده	The charge transfer complex (CT) of deferiprone (D) with iodine has been investigated spectrophotometrically in different solvents such as chloroform, dichloromethane (DCM) and 1,2- dichloroethane (1,2-DCE). The continuous variation method clearly revealed the formatin of 1:1 charge transfer complex in solution. The observed time dependence of the charge transfer band and subsequent formation of I3-in solution were related to the slow transformation of the initially formed 1:1 D.I2 outer complex to an inner electron donor-acceptor (EDA) complex, followed by fast reaction of the inner complex with iodine to form a triiodide ion. The pseudo-first-order rate constants nonlinear for the slow steps were evaluated from the absorbance-time data at 363 nm. The formation constants (KCT) and molar extinction coefficient (εCT) of the ct complexes were determined using the Benesi-Hildebrand equation. The results indicate by job‘s method of the continuous variations between donor and acceptor at maximum absorption wavelength (363nm). The spectra recorded for the complexes between iodine and deferiprone was time dependent. The subsequent formation of I3- in solution probably related to the transformation of the initially formed deferiprone: I2 outer complex to an inner complex followed by a fast reaction of the inner complex with iodine to form a tri-iodide ion. The formation constants (KCT) and molar extinction coefficient (εCT) of the CT complexes were determined using the Benesi-Hildebrand equation
پژوهشگران	معصومه حسنی موسوی (نفر اول)، سمیه ولیزاده (نفر دوم)، رضا آزادبخت (نفر سوم)