مشخصات پژوهش

عنوان	A Green Electrochemical Method for the Synthesis of Acetaminophen Derivatives
نوع پژوهش	مقاله چاپ‌شده در مجلات علمی
کلیدواژه‌ها	,Green chemistry, Electrochemical Method, electrosynthesis Acetaminophen Derivatives
چکیده	Electrochemical synthesis of new acetaminophen derivatives (4a-4c) has been carried out by the electrochemical oxidation of acetaminophen, N-(4-hydroxyphenyl)acetamide, in the presence of arylsulfinic acids (3a-3c) as nucleophiles in aqueous solution using cyclic voltammetry. The results revealed that the electrochemically generated N-acetyl-p-benzoquinone-imine (2) participates in Michael type addition reaction with arylsulfinic acids via an EC mechanism and is converted to the acetaminophen derivatives (4a-4c). The present work has led to the development of a facile and environmentally friendly reagent-less electrochemical method with high atom economy and safe waste under green conditions.
پژوهشگران	داود نعمت الهی (نفر اول)، شیما مومنی ازندریانی (نفر دوم)، صادق خزل پور (نفر سوم)