Background: the presence of heavy metal in water and soil caused by industrial activities can treat environment and human health. Stability and aggregation properties of heavy metals in living tissue caused to various diseases. Hen egg is as a susceptible food for this contamination. The present study determined lead and cadmium concentration in marketed hen eggs in Hamedan. Materials & Method: The hen eggs were collected from the various local super markets in Hamedan, Iran. Humidity percent of samples was measured and then withe ash of samples obtained by electrical furace in 550 C°. Obtained ash dissolved by 1 ml concentrated nitric acid. Flaming atomic absorption used for determination of lead and cadmium concentrations. Results: The average of lead and cadmium concentrations in samples was 0.007 ± 0.001 and 0.3± 0.08 mg/kg, respectively. The detected contents of lead and cadmium elements were lower than standard limits of WHO in hen egg. Conclusion: It is concluded that lead and cadmium concentrations in offered hen eggs in Hamedan aren’t worrisome.