This study investigated relationships among multiple intelligence,cultural intelligence, language learning strategy use, and listening comprehension of Iranian EFL learners. One hundred and ten Iranian EFL learners participated in this study. The participants completed three questionnaires and one sample of listening comprehension test: The Multiple Intelligence Questionnaire(Walter McKenzie,1999), theCultural Intelligence Questionnaire (Ang, et al. 2007),), the Strategy Inventory for Language Learning (Oxford, 1990) and a sample of Listening Comprehension test(Cambridge ESOL,2013) were selected. The results of Pearson correlation analyses revealed listening comprehension was significantly related to the multiple intelligence, cultural intelligence,and language learning strategy use. The results of multiple regression analysis showed that, multiple intelligence among the variables of the study was a stronger predictor of listening comprehension. Moreover, the findings indicated that among the components of strategy use, metacognitive strategy was the best predictor of L2 achievement.