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Abstract
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Multicomponent reactions (MCRs) are referred to one-pot, convergent chemical reactions utilizing more than two starting materials, where final product retains significant portions of all starting materials. This advanced approach has emerged as an efficient, economical, and eco-friendly substitute for conventional sequential multi-step synthesis of various biologically active pharmacophores [1]. In this study, first biochar was produced from air-dried walnut shells [2]. Then, the surface of this nano-substrate was functionalized with amine. then Knoevenagel–Michael cyclocondensation of aryl aldehydes, malononitrile, and resorcinol were performed in the presence of biochar functionalized amine at room temperature in excellent yields and very short reaction times.
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