Research Info

Home /Application of ammonium ...
Title Application of ammonium acetate as dual role reagent-catalyst for the synthesis of hybrid pyridines with triazole and sulfonamide moieties
Type Presentation
Keywords Ammonium acetate, Pyridine, Sulfonamide, Triazole
Abstract Pyridine families as the unique N-heterocyclic compounds have an important role in many natural products, pharmaceutical active molecules, agricultural compounds, organic synthesis, supramolecular chemistry, functional materials, and catalytic systems [1-2]. The fantastic properties of pyridines such as HIV protease inhibitor and anticancer, anti-inflammatory, are well known for the many of pharmocological researchers [3]. Moreover, sulfonamides as the most important organosulfur compounds by irreplacable properties including high stability and three-dimensional shape, have exceptional advantages such as having good potential in antibiotic compounds, antimicrobials, anti-bacterial, anti-inflammatory and anti-protozoal [4-5]. On the other hand, triazole scaffolds have several applications in drug systems, dyes, chemosensors, metal complexes, organocatalysts and energetic materials [6]. In our study, we synthesize new hybride pyridines with triazole and sulfonamide moieties by applying ammonium acetate as dual role reagent-catalyst.
Researchers Meysam Yarie (Third Researcher), ma z (Second Researcher), MORTEZA TORABI (First Researcher)