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Abstract
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Design and synthesis of novel and efficient catalysts in organic transformations constantly is a developing trend and an attractive challenge in chemical reactions. This perspective is a promising approach among chemists. Heterogenization of organic catalysts by using solid supports is an attractive and benefit strategy for the design of novel and lucrative catalytic systems. Magnetic catalysts are one of the most important categories of heterogeneous catalyst [1-2]. As a sequence, Fe3O4 nanoparticles have excellent adjustable functionality, large surface area ratio, excellent magnetic properties and can be modified by many organic compounds. Hereupon, magnetic catalysts are applied in photocatalysis, chiral catalysis, oxidation reactions, photoelectrochemical catalysis, multicomponent reactions, enzyme catalysis and coupling reactions [3]. Dihydropyrimidinones as a prevalent family of N-heterocycle compounds have been incorporated in many areas of chemistry such as materials science, medicinal chemistry, chemical biology and chemistry of metal complexes of ligands. These materials have been created intensive progress in pharmacological researches [4-5]. In this study, we focused on the synthesis of Biginelli-type of dihydropyrimidinones in the presence of porous polymer functionalized Fe3O4 nanoparticles (Scheme 1).
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