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Abstract
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Over the past decade, metal-organic frameworks (MOFs) are known as a porous material that has attracted the attention of many researcher groups and industries. These materials consist of multifunctional organic materials bind to metal or metal clusters through coordinated components such as carboxylates to form crystalline materials with high surface area and high thermal stability. Due to their high design capability in their structures, that is many applications in separation, storage, magnetic resonance imaging (MRI), adsorption and desorption, catalytic, drug delivery and power save [1-2]. Multi-component reactions (MCRs) have been considered as a suitable method for the preparation of many organic and pharmacologically highly biologically active compounds [3]. However, some of these methods are associated with limitations such as the use of expensive raw materials, harsh reaction conditions, long reaction times, and low efficiencies. Therefore, the development of an efficient and versatile catalyst is still needed. Compounds with N-SO3H bonds have been used as efficient catalysts and/or reagents in synthesis of organic molecules [4]. According to the strategy for developing of biologically active compounds, we wish to report Co-MOF-71/Imidazole/SO3H as metal-organic frameworks as catalyst for the synthesis of novel pyrazolo[3,4-b]pyridine derivatives under solvent-free and green conditions via CVABO mechanism (Scheme 1).
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