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Title Synthesis of 2-Amino-6-(1H-Indol-3-yl)-4- Phenylnicotinonitriles and Bis(Indolyl) Pyridines Using a Novel Acidic Nanomagnetic Catalyst via a Cooperative Vinylogous Anomeric-Based Oxidation Mechanism
Type JournalPaper
Keywords 2-Amino-6-(1H-indol-3-yl)-4- phenylnicotinonitrile; bis(indolyl) pyridine; cooperative vinylogous anomeric-based oxidation; multicomponent reaction; nanomagnetic catalyst
Abstract In the presence study, we reported the synthesis of a novel acidic nanomagnetic catalyst by supporting the prepared urea-based ligand onto the surface of Fe3O4@SiO2 nanoparticles. Afterwards, characterization of prepared recoverable catalyst was made by several methods, such as Fouriertransform infrared (FT-IR) spectroscopy, energy-dispersive X-ray (EDX) spectroscopy, elemental mapping, scanning electron microscopy (SEM), transmission electron microscopy (TEM), thermogravimetry/derivative thermogravimetry (TG/DTG), and vibrating-sample magnetometry (VSM). We investigated its catalytic performance for the synthesis of new series of 2- amino-6-(1H-indol-3-yl)-4-phenylnicotinonitriles and also bis(indolyl) pyridine derivatives through a cooperative vinylogous anomeric-based oxidation mechanism.
Researchers Yunlong Li (Not In First Six Researchers), Majid Rezaeivala (Fifth Researcher), ma z (Fourth Researcher), (Third Researcher), Meysam Yarie (Second Researcher), (First Researcher)