|
Title
|
Detection and Genomic Characterization of Canine Circovirus in Iran
|
|
Type
|
JournalPaper
|
|
Keywords
|
Iran; canine circovirus; non-diarrheic dogs; rectal swabs.
|
|
Abstract
|
Canine circovirus (CaCV) is a single-stranded DNA virus that globally circulates in dogs and wild carnivores. Although the pathogenic potential of the virus has not been fully understood yet, CaCV has been suggested to exacerbate the clinical course of other canine viral infections but also to circulate in dogs without clinical signs. In this study, we carried out real-time PCR assays to detect enteric pathogens from 156 canine rectal swabs collected from dogs without enteritis in 3 different regions in Iran. A total of 14 samples tested positive for CaCV and full-length genome sequences were obtained from 6 of the detected strains. Sequence and phylogenetic analyses showed that, despite the distance between the different sample collection sites, all Iranian CaCV strains were closely related and formed a separate clade from extant CaCVs. The present study shows that CaCV is circulating in non-diarrheic dogs in Iran, thus highlighting the need for further epidemiological investigations in Iranian domestic and wild carnivores.
|
|
Researchers
|
Linda Amarachi Ndiana (Second Researcher), Salman Zafari (Not In First Six Researchers), Francesco Pellegrini (Not In First Six Researchers), Farzad Nemati (Fifth Researcher), Paolo Capozza (Fourth Researcher), Nicola Decro (Not In First Six Researchers), Vito Martella (Not In First Six Researchers), Gianvito Lanave (Not In First Six Researchers), Reza Faraji (Not In First Six Researchers), Roberta Cardone (Not In First Six Researchers), Seyed Masoud Zolhavarieh (Not In First Six Researchers), ALIREZA SAZMAND (Third Researcher), Fazad Beikpour (First Researcher)
|