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Title
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Efficient Synthesis of β-Acetamido Ketones and Esters Using Aluminum Chloride as an Inexpensive and Green Catalyst
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Type
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JournalPaper
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Keywords
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β-acetamido ketone, β-acetamido ester, aluminum chloride, enolizable ketone, synthetic methods, multicomponent reactions
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Abstract
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Aluminum chloride (AlCl3) efficiently catalyzes one-pot multicomponent condensation of enolizable ketones or alkyl acetoacetates with aldehydes, acetonitrile and acetyl chloride to afford β-acetamido ketone or ester derivatives in high to excellent yields and in relatively short reaction times. Moreover, by this synthetic method, some novel β-acetamido ketones and esters (i.e. one complex structure) are prepared.
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Researchers
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Maria Merajoddin (Not In First Six Researchers), ahmadali dehghani firouzabadi (Not In First Six Researchers), Hassan Keypour (Not In First Six Researchers), (Not In First Six Researchers), Maliheh Safaiee (Fifth Researcher), Abdolkarim Zare (Fourth Researcher), m mo (Third Researcher), Ardeshir Khazaei (Second Researcher), ma z (First Researcher)
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