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Title Programming of Fe-catalyzed cascade Knoevenagel-Michaelcyclocondensation reaction: create out pseudo acridine derivatives under solvent free conditions
Type JournalPaper
Keywords Nano-Fe3O4; cascade reaction; 1,8-dioxo-decahydroacridine; heterogeneous catalyst.
Abstract Nano-ferrous ferric oxide (nano-Fe3O4) was successfully applied as an efficient and heterogeneous catalyst for the synthesis of 1,8-dioxo-decahydroacridines by the condensation reaction of dimedone with aromatic aldehydes and ammonium acetate or aniline derivatives under mild and solvent-free conditions. Also, optimization of the reaction condition was investigated using the response surface method {Central Composite Design (CCD)} compared to empirical research
Researchers Vahid Khaki Zadeh (Fourth Researcher), hadis afshar hezarkhani (Third Researcher), First-Name Last-Name (Second Researcher), Ardeshir Khazaei (First Researcher)