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Title
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Copper nanoparticles: A capable and versatile catalyst for the synthesis of diverse 1-phenyl-1H-tetrazoles from amino acids
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Type
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JournalPaper
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Keywords
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Fe3O4 magnetic nano-particles 3-Chloropropyltrimethoxysilane 4-Amino-1,2,4-triazole Cu complex Amino acid
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Abstract
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Cu nanoparticles were prepared in successive stages: preparation of the Fe3O4 magnetic nanoparticles (Fe3O4 MNPs), coating of the Fe3O4 MNPs with tetraethyl orthosilicate (Fe3O4@SiO2), functionalization of Fe3O4@SiO2 with 3-chloropropyltrimethoxysilane (CPTMS) and 4-amino-1,2,4-triazole (AT) ligands (Fe3O4@SiO2@CPTMS@AT), and the complexation of Fe3O4@SiO2@CPTMS@AT with CuCl2 (Fe3O4@SiO2@CPTMS@AT@Cu). The obtained Cu nano-catalyst was then used for the synthesis of diverse tetrazoles from the reaction of various amino acids with sodium azide and triethyl orthoformate (TEOF) in ethanol at 80 °C.
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Researchers
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(Third Researcher), davood habibi (Second Researcher), (First Researcher)
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