Research Info

Home /One-pot Synthesis of ...
Title One-pot Synthesis of 4-Aryl-NH-1,2,3-triazoles in Presence of Fe3O4@SiO2@Propyl-HMTA as a New Basic Catalyst
Type JournalPaper
Keywords Catalyst · Cycloaddition · Henry Reaction · Synthesis · Triazoles
Abstract In this paper, hexamethylenetetramine-functionalized magnetic Fe3O4 nanoparticles (Fe3O4@SiO2@Propyl-HMTA) catalyst was prepared and utilized for the synthesis of 4-aryl-NH-1,2,3- triazole derivatives. Also, the interaction between aldehyde, nitromethane, and sodium azide was investigated within the synthesis route. Henry Reaction between the aldehyde and nitromethane created an intermediate that was immediately attacked by N3 @. As a result of this attack, 4-aryl-NH-1,2,3- triazole was generated through an in situ [3 + 2] cycloaddition.
Researchers (Third Researcher), Ramin Ghorbani-Vaghei (Second Researcher), (First Researcher)