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Abstract
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Activity and reusability of a catalyst should be considered in designing of it. Homogenous catalysts have higher activity than heterogeneous catalysts, but their separation and recycling is more difficult than heterogeneous ones. On the other hand, activity of heterogeneous catalysts is low, however their separation and reusability is easy [1]. 1-Amidoalkyl-2-naphtols have biological importance because they can be converted to 1,3-oxazine [2]. 1,3-Oxazine derivatives have pharmaceutical and biological properties such as anti-tumor, anticonvulsant, antimalarial, analgesic, antibiotic, antianginal, antirheumatic and antihypertensive [3-5]. Herein, we wish to introduce [Fe3O4@SiO2@(CH2)3-im-CH2CO2H]Br as a novel nano magnetic catalyst and use it as an efficient and reusable catalyst in the synthesis of amidoalkyl phenols under solvent-free condition
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