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Title
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Electrochemical Synthesis of a New Derivative of 1,4-Dihydroxybenzene: Embedded Nucleophile in the Structure of Electrophile
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Type
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JournalPaper
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Keywords
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Electrochemical Synthesis Dihydroxybenzene Electrophile
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Abstract
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In this work the electrochemical oxidation of 4-(Piperazin-1-yl)phenols (1a,b) was studied in the water, acetonitrile and nitromethan by means of cyclic voltammetry and controlled-potential coulometry. The results revealed that p-quinone-imines generated of oxidation 4-(Piperazin-1-yl)phenols after the hydrolysis reaction participate in Michael-addition reactions with released piperazine of hydrolysis reaction of p-quinone imines. The present work has led to the development of a facile and environmentally friendly electrochemical method for the synthesis of a new derivative of 1,4-dihydroxybenzene under green conditions. In addition, the effect of water as a solute on the electrochemical response of 4-(Piperazin-1-yl)phenols (1a,b) was examined in the acetonitrile (AN) and nitromethane (NM) solvent.
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Researchers
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Sadegh Khazalpour (Not In First Six Researchers), Davood Nematollahi (Fifth Researcher), Maryam Rajabi (Fourth Researcher), Amaneh Amani (Third Researcher), alireza Asghari (Second Researcher), (First Researcher)
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