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Title
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Application of the Fe3O4@1,10‐phenanthroline‐5,6‐diol@Mn nano‐catalyst for the green synthesis of tetrazoles and its biological performance
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Type
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JournalPaper
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Keywords
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1,10‐phenanthroline‐5,6‐diol, biological performance, catalyst, Fe3O4 magnetic particle, tetrazoles
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Abstract
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The Fe3O4 magnetic particles were modified with 1,10‐phenanthroline‐5,6‐diol (Phen) and the related Mn complex (Fe3O4@Phen@Mn) synthesized as a heterogeneous catalyst to be used for the one‐pot three‐component synthesis of various tetrazoles. The catalysts were characterized by several methods, such as the elemental analysis, FT‐IR, X‐ray powder diffraction, dispersive X‐ray spectroscopy, scanning electron microscopy, transmission electron microscopy, dynamic light scattering, thermogravimetric‐differential thermal analysis, vibrating sample magnetometer and X‐ray photoelectron spectroscopy. In addition, the antioxidant and antibacterial activities of the catalyst and its Phen ligand were in vitro screened with 2,2‐diphenyl‐1‐picrylhydrazyl by free radical scavenging methods. Results showed that the synthesized compounds possess strong antioxidant activity (IC50; 0.172 ± 0.005 mg ml−1) as well as a good antibacterial potential in comparison to standards.
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Researchers
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Mostafa Asadbegy (Not In First Six Researchers), Roya Karamian (Not In First Six Researchers), (Fifth Researcher), (Fourth Researcher), Antonio Gil (Third Researcher), (Second Researcher), davood habibi (First Researcher)
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