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Abstract
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Nowadays Xanthene and Dibenzo-xanthens derivatives are very important because of their antibacterial, antiviral and anti-inflammatory properties and have extensive use in biological and medical fields. [1,2]. The other useful applications of these heterocycles are as leucodyes and in laser technologies [3]. Furthermore, electrochemistry offers many novel and versatile methods for the study of electroactive compounds in pharmaceutical forms due to their simple, rapid, and economical properties. As an electroactive substance, dibenzo-xanthene derivatives has also attracted much interest. In this work, the electrochemical behavior of some aryl-5H-dibenzo[b,i]xanthene-5,7,12,14(13H)-tetraone derivatives (ADBXT), has been studied using cyclic voltammetry and differential pulse voltammetry. The cyclic voltammograms of these compounds display two redox peaks correspond to the reduction of two p-benzoquinone rings presence in the structure of the molecule to the corresponding hydroquinone forms. It was also found that the presence of hydroxy group on the phenyl ring is an effective factor in electrochemical behavior of these molecules. Based on our voltammetric data, the electrochemical oxidation of 4-hydroxy and 3-hydroxy phenyl derivatives exhibits an irreversible anodic peak (A2) at +1.03 V versus Ag/AgCl correspond to the oxidation of phenol substituent on molecule, while this peak is not observed for other derivatives. In addition, the effect of potential scan rate, on the cyclic voltammetric response in anodic region confirms the irreversibility of the oxidation process corresponding to peak A2. Furthermore, the effect of pH and adsorption activity of ADBXT derivatives was also studied.
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