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Abstract
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Electro-organic synthesis has recognized as a powerful tool to develop environmentally compatible processes. It is characterized by high selectivity, readily available starting materials, good atom economy, low-energy consumption and temperature, low-cost reagents and material failure. Furthermore, electrons are considered to be clean reagents [1]. Diphenyl disulfone is a mild and efficient reagent for selective cleavage of methylprenyl (2,3-dimethylbut-2-en-1-yl), prenyl (3-methylbut-2-en1yl), and methallyl (2 -methylallyl) ethers [2]. Several methods have been reported for the synthesis of diphenyl disulfone derivatives, including the oxidation of benzenesulfinic acid by KMNO4 [3], and Cobalt (III) [4], and etc. However, these methods have the disadvantages such as low yield, poor purity, lack of easy availability/preparation of the starting materials, tedious work-up, heavy metal pollution, strongly acidic media and safety problems. These disadvantages have motivated us to develop a green protocol for the synthesis of diphenyl disulfones by electrochemical oxidation of aryl sulfinic acids in aqueous solution. This work leads to a straight-forward methodology for the synthesis of diphenyl disulfones by an environmentally friendly method in ambient conditions and in an undivided cell.
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