|
Title
|
Synthesis of pyrano[2,3-c]pyrazole derivatives using Fe3O4@SiO2@piperidinium benzene-1,3-disulfonate (Fe3O4@SiO2 nanoparticle-supported IL) as a novel, green and heterogeneous catalyst
|
|
Type
|
JournalPaper
|
|
Keywords
|
Fe3O4@SiO2@piperidinium benzene-1,3-disulfonate; pyrano[2,3-c]pyrazole; water solvent
|
|
Abstract
|
A simple, green and efficient protocol for the one-pot four-component synthesis of pyrano[2,3-c]pyrazole derivatives produced from reaction between aryl aldehydes, ethyl acetoacetate, malononitrile and hydrazine hydrate in the presence of nano magnetic piperidinium benzene-1,3-disulfonate was synthesized in water at 60 °C. The Fe3O4@SiO2 nanoparticle-supported IL was designed and synthesized. The present process offers advantages such as clean reaction, short reaction time, good to excellent yield, easy purification and easy recoverable catalyst. Copyright © 2017 John Wiley & Sons, Ltd.
|
|
Researchers
|
(Fourth Researcher), (Third Researcher), (Second Researcher), Ramin Ghorbani-Vaghei (First Researcher)
|