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Title Efficient synthesis of novel quinazoline-4(1H)-one derivatives by N-halosulfonamides
Type JournalPaper
Keywords poly(N-bromo-N-ethylbenzene-1,3-disulfonamide) ,N,N,N′,N′-tetrabromobenzene-1,3-disulfonamide, quinazoline-4(1H)-one ,Iso toic anhydrid,acid hydrazide
Abstract In this research, a facile, effective and one-pot synthesis of new quinazoline-4(1H)-one derivatives is reported. Isatoic anhydride, acid hydrazides or ammonium acetate and aromatic aldehydes in the presence of N-halosulfonamides; N,N,N′,N′-tetrabromobenzene-1,3-disulfonamide and poly(N-bromo-N-ethylbenzene-1,3-disulfonamide) are used to produce the above-mentioned compounds. In addition, the reaction medium is in agreement with green chemistry principles. Graphical Abstract
Researchers (Fourth Researcher), (Third Researcher), (Second Researcher), Ramin Ghorbani-Vaghei (First Researcher)