Title
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In this study, one-pot diastereoselective three-component reaction of urea/thiourea, 2,3-dihydrofuran/3,4-dihydro-2H-pyran with aromatic aldehydes have been developed for synthesis of hexahydrofurano and hexahydropyrano pyrimidinones (thiones) using poly(N-bromo-N-ethyl-benzene-1,3-disulfonamide) [PBBS] and N,N,N',N'-tetrabromobenzene-1,3-disulfonamide [TBBDA].
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Type
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JournalPaper
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Keywords
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N-halosulfonamides, spirocycles, Michael addition, cyclopropane, indane-1,3-dione, ring closure
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Abstract
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In this study, one-pot diastereoselective three-component reaction of urea/thiourea, 2,3-dihydrofuran/3,4-dihydro-2H-pyran with aromatic aldehydes have been developed for synthesis of hexahydrofurano and hexahydropyrano pyrimidinones (thiones) using poly(N-bromo-N-ethyl-benzene-1,3-disulfonamide) [PBBS] and N,N,N',N'-tetrabromobenzene-1,3-disulfonamide [TBBDA].
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Researchers
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(Second Researcher), Ramin Ghorbani-Vaghei (First Researcher)
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