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Title
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Transition metal‑free synthesis of quinolino[2′,3′:3,4] pyrazolo[5,1‑b]quinazolin‑8(6H)‑ones via cascade dehydrogenation and intramolecular N‑arylation
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Type
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JournalPaper
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Keywords
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Quinoline · Quinazolinone · Intramolecular N-arylation · Cascade reaction · Polyheterocycles · Transition metal-free
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Abstract
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2-(2-Chloroquinolin-3-yl)-3-(arylamino)- 2,3-dihydroquinazolin-4(1H)-one was converted to quinolino[ 2′,3′:3,4]pyrazolo[5,1-b]quinazolin-8(6H)-ones in the presence of KOtBu in DMSO at room temperature. The present method has the advantages of easy conditions, construction of highly novel five heterocycles, transition metalfree conditions, cascade dehydrogenation and intramolecular N-arylation and good to high yield of products
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Researchers
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Neil Koorbanally (Not In First Six Researchers), Suhash Shintre (Not In First Six Researchers), Atefeh Nejatnejad (Not In First Six Researchers), (Fifth Researcher), ma z (Fourth Researcher), Hoda Hamidi (Third Researcher), Majid Heravi (Second Researcher), First-Name Last-Name (First Researcher)
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