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Title One-pot multi-component synthesis of 1,2,4,5-tetrasubstituted imidazoles using sulfonic acid-functionalized pyridinium chloride as an ecient and recyclable catalyst
Type JournalPaper
Keywords 1,2,4,5- tetrasubstituted imidazole; Sulfonic acidfunctionalized pyridinium chloride f[Pyridine-SO3H]Clg; Ionic liquid; Solvent-free; Benzyl; Primary amine; Aldehyde.
Abstract Sulfonic acid-functionalized pyridinium chloride ionic liquid f[Pyridine- SO3H]Clg can e ectively promote the one-pot multi-component condensation reaction between benzil, aldehydes, primary amines, and ammonium acetate under solvent-free conditions at 100C to give the desired 1,2,4,5-tetrasubstituted imidazoles in high yields and short reaction times
Researchers Abdolkarim zare (Third Researcher), z a (Second Researcher), ma z (Fourth Researcher), First-Name Last-Name (First Researcher)