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Abstract
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Abstract Toxoplasma gondii is one of the major agents of infectious abortions and, due to its worldwide distribution, can threat healthy pregnant women who had no previous exposure to this parasite. The present study was designed to determine the titer of anti-toxoplasma antibody in women with history of abortion visiting Hamedan’s medical centers during 2012– 2013. Blood samples were collected from 300 mothers with previous history of abortion coming to the provincial medical centers during the period spanning October 2012 to June 2013. The sera were isolated and subjected to evaluate the anti-toxoplasma IgG antibodies using ELISA method. The result showed IgG positive (IgG+) in 111 cases (37 %); the highest prevalence of T. gondii IgG antibodies was seen in the age of 24–27 years, while the age group 32–39 showed the lowest IgG seroprevalence (3.6 %). Among women with history of abortion, the highest abortion rate (25 %) was seen in the age of 8 weeks (first trimester of pregnancy). Possible routes of infection were contaminated soil, eating raw vegetables rather than eating uncooked meat, or contact with cat. More women from rural areas (63.96 %) had more IgG antibodies to T. gondii than urban women (36.03 %). According to our finding, 63%of aborted women were serolonegative and at risk of congenital toxoplasmosis for their fetuses. Hence, it is necessary for health policy makers to design the preventive measures against congenital toxoplasmosis
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