The large-scale atmospheric-oceanic phenomena are among the main effective factors in the droughts in the Middle East, especially in Iran. Since these effects are usually delayed, their relevant signals can be useful for predicting droughts. As a result, the provision of a precise prediction of these signals can be efficient in increasing the drought prediction prospect. The current study predicts 8 cases of the most effective oceanic signals on the droughts which have been investigated in Iran. To do so, the problem-solving method with the time series prediction approach is based on the two model types intelligence-based (including multilayer perceptron [MLP] and support vector machine [SVM]) and stochastic (including Autoregressive Integrated Moving Average [ARIMA]) has been used. The model’s input for each index included the time lags of the same index itself, which was determined by the autocorrelation function. Based on the evaluation criteria, the results were indicative of the weak predictability of the North Atlantic Oscillation (NAO) and Arctic Oscillation (AO), while the Extreme Eastern Tropical Pacific sea surface temperature (Nin˜o [1 + 2]), East Central Tropical Pacific sea surface temperature (Nin˜o [3 + 4]), and Oceanic Nin˜o Index (ONI) were predicted with very good accuracy, and there is a high overlap between their predictions and observations (95.9 % < R2 < 99.3 %). In the extreme events also, the rate of normalized forecasting error for Nin˜o (1 + 2), Nin˜o (3 + 4), and ONI were in the medium (20–30 %), good (10–20 %), and excellent (0–10 %) ranges, respectively. The comparison between the models also indicates a partial superiority of the ARIMA stochastic model over the SVM and MLP models. The overall results of the study are indicative of the applicability of the predictions of the three mentioned indices as the inputs to increase precipitation and drought forecasting prospects in Iran (as well as all regions affected by them); which have the r