In recent years, magnetic nanomaterials, such as iron oxide nanoparticles, have attracted great attention in different fields including Analytical Chemistry. Due to their magnetic properties, low-cost, and excellent biocompatibility, iron oxide nanoparticles have a wide application as adsorbents in food analysis, bioanalysis, environmental monitoring, forensic chemistry, and magnetic digital microfluidics as well as colorimetric sensors, resonance light scattering sensors, surface-enhanced Raman spectroscopy sensors, electrochemical sensors, and biosensors. Various chemical methods have been developed for the synthesis of iron oxide nanoparticles such as sol- gel, microemulsion, thermal decomposition, and coprecipitation, hydrothermal/solvothermal, sonochemical, and electrochemical methods. Furthermore, they can be easily functionalized using polymer coatings including MIP and IIP layers, nanocomposites, nanoparticles immobilizations, and anchoring functional moieties. In Analytical Chemistry, magnetic nanomaterials can be utilized in methods such as magnetic solid-phase extraction, magnetic headspace-adsorptive extraction, magnetic in-tube extraction, cloud point-magnetic dispersive-SPE, electrochemical methods, and Resonance light scattering.
