Construction of liquid marbles for miniaturized synthesis has recently attracted extensive attention due to numerous potential applications. However, manufacturing liquid marble-based microreactors to carry out chemical reactions that required a long time for completion is a challenge. In this study, sulfur-stabilized liquid marbles submerged at the interface of aqueous-organic biphasic systems were used as miniature reactors to carry out chemical reactions. Various chemical reactions have been carried out including, polymerization, reduction, hydrolysis and metal-organic framework (MOF) formation. This approach provides a suitable platform to performed reactions at the liquid marbles interface. Due to the solubility of sulfur particles around the liquid droplets in the organic liquids, a new interface is provided for the reactions. Submerging the sulfur-stabilized liquid marbles in biphasic systems leads to an increase in microreactors’ lifetime. The lifetime of sulfurstabilized liquid marbles depends on the type of organic solvent and the amounts of pre-dissolved sulfur in organic phase as well.
