The distribution and overuse of chemical fertilizers in Iran are still a considerable issue, so further research is needed to gain a deeper understanding of the challenge. Accordingly, modifying farmers’ ineffi cient behaviors toward the use of chemical fertilizers (UCFs) is a policy initiative taken by all countries to achieve sustainable agriculture, but the rate of adoption by stakeholders is a challenge, yet has the potential to be under study. Employing 375 potato farmers in Hamedan County, western Iran, the present research mainly inves‑ tigated driving factors that account for and give new information about farmers’ behav‑ ior toward the UCFs, Iran, where a substantial volume of agriculture products is produced in this district. The developed theory of planned behavior served as a predicting theoreti‑ cal foundation to accomplish so. The resulting evidence made clear that 60 percent of the variance in farmers’ behaviors of the UCFs is forecasted by the two constructs of farmers’ intention and knowledge. This study concludes that farmers’ behavior toward the UCFs is needed to be adjusted by providing farmers with the required knowledge and information.