Mesoporous materials, due to their unique textural and structural features and successful applications in different scientific areas engrossed our curiosity to form a mesoporous nanostructure. A facile method for the formation of polymer support nanostructures was designed and further modified with chlorosulfonic acid poly(triazine-benzene sulfonamide)-SO3H (PTBSA-SO3H). It catalyzed the formation of 1,8-naphthyridine derivatives for the six runs. The current strategy provided a wider substrate range, and short reaction times.