In this research, a facile, effective and one-pot synthesis of new quinazoline-4(1H)-one derivatives is reported. Isatoic anhydride, acid hydrazides or ammonium acetate and aromatic aldehydes in the presence of N-halosulfonamides; N,N,N′,N′-tetrabromobenzene-1,3-disulfonamide and poly(N-bromo-N-ethylbenzene-1,3-disulfonamide) are used to produce the above-mentioned compounds. In addition, the reaction medium is in agreement with green chemistry principles. Graphical Abstract
