In this paper, we aimed at synthesizing GO/H2L-Pd nano-composites (graphene-oxide/schiff base N2O4 Ligand-palladium) as a new heterogeneous catalyst. Moreover, different analytical techniques were applied in order to analyze the chemical composition and the structure of the catalyst. In synthesizing the furan derivatives via one-pot three-component condensation reaction of different aromatic aldehydes, arylamine and acetylenedicarboxylate in ethanol, we witnessed good to excellent yields of GO/H2L-Pd catalyst. Accordingly, regarding industrial applications, it can be said that the results of this study can be used in growing a novel class of heterogeneous catalysts.