رامین قربانی واقعی

In this project, a series of nano catalysts including magnetic nanoparticles Fe3O4, ZnFe2O4, Ni0.5Zn0.5Fe2O4, acidic functionalized carbon nano tube SWNT-COOH, nano MgO and nano Al2O3 have been prepared and their catalytic activities in the synthesis of five and six-membered heterocyclic compounds have been studied. Also, synthesis of some heterocyclic compounds under solvent-free conditions has been investigated. This project was performed in four experimental parts as follows: In part 1, synthesis of 1,4-dihydropyridines derivatives, in the presence of acidic functionalized carbon nano tube SWNT-COOH has been examined. This nano-catalyst can be easily recovered via centrifuges and reused without any significant drop in its catalytic activity. In part 2, synthesis and investigation of catalytic activity of nano-magnetic ferrites such as Fe3O4, ZnFe2O4 and Ni(0.5)Zn(0.5)Fe2O4 have been studied in the synthesis of pyranopyrimidines, pyrazolophthalazines, pyridopyrimidines and indazolophetalazines. It was observed that, among synthesized magnetic nanoparticles, nano-magnetic ferrite ZnFe2O4 is the most effective catalyst for synthesis of pyranopyrimidine and pyrazolophthalazines. It was found that, the catalytic power of various spinel ferrites examined in the mentioned reactions is related to the structural isotropy, cation distribution and the Lewis acid character of the cations embedded in the structures of these ferrites. In continuos, in part 3, nano Al2O3 has been explored as an efficient and recyclable catalyst for the synthesis of pyranochromene derivatives at room tempreture. At the end, in part 4, in the synthesis of pyrazolopyridazin, nano-MgO has been used as an effective catalyst and its catalytic activity has been studied. High surface area and easy recyclability of these catalysts, solvent-free conditions, easy preparation of the catalysts, low reaction times and high yields of the products are the main advantages of this methods.